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This is a lesson where learners are introduced to chemical change and the conservation of matter during different types of chemical changes. The lesson models scientific inquiry using the 5E instructional model and includes teacher notes, prerequisite concepts, common misconceptions, student journal and reading. This is the fourth lesson in the Astro-Venture Atmospheric Science Training Unit. The purpose of the unit is to increase students' awareness of and interest in astrobiology and the many career opportunities that utilize science, math and technology skills. The lessons are designed for educators to use in conjunction with the Astro-Venture multimedia modules.