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In this activity, learners will explore the question, What is the chance that we are the only life in the universe? They determine what we need to know to predict the chances of extraterrestrial life. They then make estimates of the number of worlds in the Milky Way galaxy that have life using the Drake equation. This is activity 5 of 5 in "Astrobiology in your Classroom: Life on Earth..and Elsewhere?" and builds on the previous activities.